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The true potential of peptide therapy for skin health

We take a closer look at what it is, how it works, and whether or not it’s for you.

By LLM Reporters   |  

Modern skincare is becoming increasingly sophisticated, with cutting-edge treatments and techniques emerging seemingly by the day. But every so often, something comes along that really changes the game, and peptide therapy might just be one of them.

The innovative therapyhas been making waves in recent years as a powerful solution for improving skin health and is favoured by a host of notable celebrities as well as beauty industry experts, being heralded as the secret weapon we’ve all been waiting for in the fight against the signs of aging.

Peptides, which are short chains of amino acids, are being embraced for their ability to support collagen production, enhance cell communication and deliver targeted anti-aging benefits such as enhanced plumpness of the skin and a reduction in the appearance of fine lines and wrinkles.

In a recent discussion on YouTube, Dr Craig Koniver, a leader in performance medicine, and renowned neuroscientist Andrew Huberman, talked about how innovative uses of peptides could transform skin care, as well as health in general.

By unlocking the science behind these bioactive molecules, we can better understand how peptide therapy can change the future of skincare. Here, we take a closer look at what it is, how it works, and whether or not it’s for you.

Understanding peptides in skin care

peptide in a bottle, chemical ingredient in beauty product, skin care products
Peptides are naturally occurring molecules that play a critical role in skin health by acting as messengers between cells, signalling the body to produce more collagen, elastin and other proteins key for maintaining a youthful complexion

Peptides are naturally occurring molecules that play a critical role in skin health by acting as messengers between cells, signalling the body to produce more collagen, elastin and other proteins key for maintaining a youthful complexion. Peptides are typically small chains of amino acids that are foundational to the structure of proteins in the skin – particularly collagen. This substance is responsible for keeping skin firm and smooth, but the body’s natural production of collagen slows as we age, which can lead to sagging, fine lines and wrinkles – so it’s vital that we replenish it through our skincare.

There are several types of peptides used in skincare, each with a different function. Collagen peptides stimulate collagen production, helping to reduce wrinkles and improve skin elasticity, while carrier peptides, known for delivering trace elements like copper to the skin, support wound healing and repair. Then, there are neurotransmitter peptides, which work by blocking the release of chemicals that cause muscle contractions, acting similarly to Botox to reduce expression lines, but without the toxins.

By incorporating these peptides into your daily skincare routine, it’s possible to target specific skin concerns like fine lines, hyperpigmentation and loss of firmness, so it’s easy to see why for many, they’re becoming a non-negotiable.

Stacking peptides

Pipette with essential oil, serum with peptides, emulsion, hyaluronic acid on beige background.
Pipette with essential oil, serum with peptides, emulsion, hyaluronic acid on beige background. Closeup of beige dropper, falling drop of oil close up. Beauty skincare product. Self care concept

According to Dr Craig Koniver, one of the most innovative ways of leveraging the benefits of peptide therapy is known as peptide stacking – in other words,combining and administering multiple peptides to enhance the effects, which range from an all-round boost to skin health to benefits that go beyond the skin alone, such as better sleep. More specifically, Dr Koniver believes that peptide stacking with BPC-157, Ipamorelin and Tesamorelin offers a potent and powerful tonic  that increases collagen production, enhances skin healing and supports metabolic functions.

So what exactly are these particular peptides – and what’s so special about them?

Well, BPC-157 is known for its regenerative properties, and promotes tissue repair whilst reducing inflammation, making it beneficial for skin rejuvenation and healing. Ipamorelin, meanwhile, is often chosen thanks to its growth hormone-releasing properties, as it aids in anti-aging by improving collagen synthesis and cellular turnover. And tesamorelin is praised for its ability to reduce visceral fat while simultaneously improving skin elasticity and overall vitality.

Dr Koniver has developed practical protocols for incorporating peptide therapy into daily routines, with one popular approach known as the bedtime stack. This works when peptides like BPC-157 and Ipamorelin are taken before you go to sleep to promote skin repair during the body’s natural healing process, which takes place while you’re snoozing at night.

For those seeking increased vitality and enhanced skin benefits during the day, Dr Koniver recommends a morning stack, including peptides like Hexarelin, which promotes energy and stimulates collagen synthesis. By targeting both day and night cycles, these peptides work in tandem to support holistic skin and body health.

The science behind the therapy

woman looking in mirror
Peptides work by interacting with receptors on the surface of cells, triggering a range of biological responses that enhance skin health

Peptides work by interacting with receptors on the surface of cells, triggering a range of biological responses that enhance skin health. At a cellular level, peptides like BPC-157 and Ipamorelin stimulate fibroblasts, the cells responsible for collagen production, improving skin structure and elasticity over time. This cellular regeneration process is supported by clinical studies that highlight the efficacy of peptides in reducing signs of aging, improving wound healing and promoting overall skin vitality .

Peptide therapy is backed by emerging clinical evidence, with studies on specific peptides, such as GHK-Cu (a copper peptide), showing significant improvements in skin elasticity, firmness and the reduction of fine lines. Research also indicates that peptides can play a vital role in repairing UV-damaged skin, making it clear that they are a very versatile – an essential – addition to anti-aging skincare routines.

General feedback from users of peptide therapy has shown a high level of satisfaction – particularly regarding the anti-aging and vitality-boosting effects. Many people have reported improvements in skin texture, reduced fine lines and better hydration after some weeks of peptide use. The inclusion of peptides like Ipamorelin in daily protocols is frequently mentioned in conversations about enhanced sleep quality and overall wellness.

Testimonials from early adopters of peptide therapy highlight the holistic benefits beyond skincare, including better recovery after workouts, increased energy and improved fat metabolism – all of which contribute to healthier-looking.

Despite the many benefits that come with peptide therapy, it is not without its challenges. One key consideration is the importance of correct dosages, as improper use of peptides can lead to unwanted side effects such as headaches, nausea, or hormonal imbalance, so getting it right is key. This is why professional guidance is crucial when starting peptide therapy, and consulting with a healthcare provider will ensure that your treatment is tailored and administered safely.

For now, accessibility and cost are potential barriers for many consumers – but for the affluent, there is no red tape. Peptide therapy can be costly, particularly when using multiple peptides over an extended period – but many will vouch for it being worth the splurge. As it is still a relatively new area of treatment, finding qualified practitioners and sourcing high-quality peptides can also be difficult – but as peptide therapy becomes more mainstream, these barriers may diminish over time.